Khopoli, is an industrial town in the Khalapur taluka of Raigad district, in the Indian state of Maharashtra, at the base of the Sahyadri mountains. Patalganga River which is the tailrace channel of Tata Hydroelectric Power station flows through Khopoli.
It is a municipal council and is a part of the Mumbai Metropolitan Region. Khopoli Municipal council covers an area of 30 km2.
Khopoli is connected to the Mumbai suburban railway by a single line from Karjat. The distance between CST to Khopoli is 114.24 km along the Central Railway Suburban Line which is a broad gauge line carrying electric locomotives.
It is also located on NH 4, about 80 km south of Mumbai.